P04.26 * MOLECULAR MECHANISMS OF CIRCULATING MICRORNA BIOMARKERS FOR GLIOBLASTOMA
نویسندگان
چکیده
منابع مشابه
Circulating microRNA Biomarkers of Diabetic Retinopathy.
The incidence of diabetes is increasing globally, and in spite of modern treatments for glucose, blood pressure, and lipids, the vascular and neurologic complications of diabetes still occur at unacceptably high rates. The personal and economic burdens are enormous. Diabetes is a common cause for vision loss (diabetic retinopathy [DR]), renal impairment (nephropathy), peripheral and autonomic n...
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OBJECTIVE In this study, we investigated whether circulating microRNA-137 (miR-137) could be a potential biomarker for patients with glioblastoma (GBM). PATIENTS AND METHODS Serum samples were collected from 64 GBM patients and 64 healthy controls. The expression level of circulating miR-137 was compared by quantitative RT-PCR. Among GBM patients, circulating miR-137 was compared between pati...
متن کاملPlasma-based circulating MicroRNA biomarkers for Parkinson's disease.
BACKGROUND The current "gold-standard" for Parkinson's disease (PD) diagnosis is based primarily on subjective clinical rating scales related with motor features. Molecular biomarkers that are objective and quantifiable remain attractive as clinical tools to detect PD prior to its motor onsets. OBJECTIVE Here, we aimed to identify, develop, and validate plasma-based circulating microRNA (miRN...
متن کاملGenome-wide circulating microRNA expression profiling indicates biomarkers for epilepsy
MicroRNAs (miRNAs) have been proposed as biomarkers for cancer and other diseases due to their stability in serum. In epilepsy, miRNAs have almost been studied in brain tissues and in animals' circulation, but not in circulation of human. To date, a major challenge is to develop biomarkers to improve the current diagnosis of epilepsy. The aim of this study was to evaluate whether circulating mi...
متن کامل[Circulating Serum MicroRNA as Diagnostic Biomarkers for Multiple Myeloma].
OBJECTIVE To investigate the diagnostic value of circulating serum miRNA for multiple myeloma. METHODS Forty blood samples from patients with multiple myeloma were collected from July 2013 to June 2014 in Department of Hematology, Zhongshan Hospital Affiliated to Xiamen University. The real-time quantitative PCR was performed to detect the serum expression levels of miRNAs (miR-29a, miR-155, ...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2014
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/nou174.158